Clinical Trials (ECHO IDeA States Pediatric Clinical Trials Network)
Infants and children living in rural areas are less likely than those living elsewhere to have a chance to enroll in clinical research, especially clinical trials. Because of this, the ECHO Program paired with the NIH IDeA States Program to create the ECHO IDeA States Pediatric Clinical Trials Network (ISPCTN). This network ensures that children in states with historically low NIH funding have access to clinical trials as part of ECHO.
The ECHO ISPCTN is made up of research sites in 18 states. The network helps address disparities in pediatric research by including children from rural or underserved populations in clinical trials, and by building pediatric research capacity in states with historically low NIH funding.
The ECHO ISPCTN aims to enhance pediatric clinical trial access at state and national levels and to help carry out well-designed clinical trials in children. The Network has the following goals:
- Provide medically underserved and rural populations access to state-of-the-art clinical trials in ECHO’s five areas of child health.
- Build the national capacity to conduct pediatric clinical trials by providing professional development, team support and infrastructure building for ECHO researchers and other research faculty outside of ECHO.
ECHO ISPCTN researchers should visit the Team Login page to access study information and professional development.
Data Coordinating and Operations Center
The Data Coordinating and Operations Center (DCOC) manages the following activities for the ECHO ISPCTN:
- Data coordination
- Technical instruction
- Data standards
- Quality control and assurance
- Operational coordination for ECHO ISPCTN clinical trials
Principal Investigators: Matthew Mayo, Russell McCulloh, and Jo Wick
About the IDeA States Program
The Institutional Development Awards (IDeA) Program was first authorized by Congress in 1993 and is managed by the National Institute of General Medical Sciences. The IDeA States Program was developed to widen the distribution of NIH funding for biomedical and behavioral research. It is designed to enhance the competitiveness for research funding in states with historically low NIH funding.
IDeA States Pediatric Clinical Trial Network
About the ECHO ISPCTN
ECHO ISPCTN conducts intervention research making changes in participants’ lives to see how the changes affect their health.
Our Studies
Ongoing
- ACT NOW (Advancing Clinical Trials in Neonatal Opioid Withdrawal)
- INTACT (Pilot Feasibility Trial of Improving Neurodevelopmental ouTcomes After prenatal Cannabinoid in uTero exposure)
RAMP (A Pilot Study of a Remote Attention-Deficit/Hyperactivity Disorder Monitoring Program (RAMP) for Children in Rural Areas) - Talk With Me Baby (Leveraging Well-Child Care to Enhance the Early Home Language Environment for Rural and Underserved Children)
Completed
- ACT NOW CE (Advancing Clinical Trials in Neonatal Opioid Withdrawal Current Experience)
- BREATHE (Bronchiolitis Recovery and the Use of High Efficiency Particulate Air (HEPA) Filters). Recruitment is complete for this study.
- iAmHealthy (Rural Disparities in Pediatric Obesity)
- MoVeUP (Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool)
- POPS (Pharmacokinetics of Understudied Drugs Administered to Children per Standard of Care)
- VDORA1 (Vitamin D Oral Replacement in Asthma)