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Dr. Petrick: Untargeted Analysis of Microsamplers: The Utility of Dried Capillary Blood Spots for Exposome Research
February 14 @ 1:00 pm - 2:00 pm
Untargeted Analysis of Microsamplers: The Utility of Dried Capillary Blood Spots for Exposome Research
Key Takeaways:
- Researchers use blood samples to measure the levels of various chemicals and metabolites related to environmental exposures and track those exposures over time. However, it can be logistically and technically challenging to continuously collect venous blood samples over critical developmental time periods, such as early childhood.
- Dried blood microsamplers (DBMs) can be collected easily at home or in the clinic using a finger prick, providing researchers with new opportunities for direct and continuous monitoring of environmental exposures in young children and other vulnerable populations.
- A technique called untargeted liquid chromatography-high resolution mass spectrometry (LC-HRMS) can be used to accurately measure a broad range of chemicals and metabolites in dried blood microsamplers.
- A few recent pilot programs are demonstrating how DBMs can be used to capture and track environmental exposures in children and other vulnerable populations.
Speaker:
Dr. Lauren Petrick
Associate Professor at Icahn School of Medicine
Director of the Center of Metabolomics and Molecular Phenotyping at Sheba Medical Center
Speaker Bio:
Dr. Lauren Petrick is an Associate Professor at the Icahn School of Medicine at Mount Sinai, NY and the Director of the Center for Metabolomics and Molecular Phenotyping at the Sheba Medical Center, Israel. She is an analytical chemist and exposure biologist, who did her postdoctoral training at UC Berkeley. Dr. Petrick leads the Laboratory of Precision Metabolomics and Exposomics (PRIME) where her research group develops untargeted chemical assays using high resolution mass spectrometry and applies them to discover biomarkers across disease contexts. She is the Principal Investigator (PI) of several NIH grants focused on discovery of early-life causal risk factors of autism and testicular cancer.