Chemical Exposures

ECHO Chemical Exposures Research

Every day, we encounter environmental chemicals, including in our water, food, household products, and the air we breathe. The ECHO Program is dedicated to understanding how exposure to these chemicals impacts the health and well-being of children and families.

The ECHO Program’s uniquely diverse, nationwide research network includes more than 64,000 children and families. It allows researchers to investigate how chemical exposures can influence a child’s development during pregnancy and their weight, breathing, mental health, and more as they grow up. The ECHO Program explores the health effects of various chemicals, including per- and polyfluoroalkyl substances (PFAS), lead, phthalates, phenolsparabens, and others.

What We're Learning

The ECHO Program has published more than 1,500 articles about the results of its research, including many that looked at chemical exposures.

Here are recent examples of ECHO research:

 

Study Reveals Rising Levels of Plastics, Pesticides, and Replacement Chemicals in Pregnant Women
May 2022
Over 50% of women had more than one-third of the studied chemicals, and over 90% of pregnant women had one-fifth of the chemicals, showing widespread exposure.

ECHO Study Finds Link Between Phthalate Exposure and Preterm Birth, Estimates Potential Costs
February 2024
Certain phthalates were linked to a doubled risk of preterm birth in women with the highest exposure. The study also calculated the costs associated with phthalate exposure.

ECHO Research Suggests Airborne Lead Exposure Affects Children’s Cognitive Development, Impacting Males More Than Females
March 2024
Children who lived in areas with relatively more lead pollution in the air in the early years of their lives exhibited less impulse control and had slightly lower IQ scores when they reached preschool and school age.

ECHO Study Finds Flame-Retardant Chemicals May Increase Risk Of Preterm Birth and Higher Birth Weight
January 2024
Pregnant individuals exposed to specific classes of flame retardants may face an increased risk of preterm birth, especially for baby girls and babies with higher birth weights

Maternal PFAS Exposure During Pregnancy May Increase Children’s Risk of Obesity
June 2023
Higher levels of some PFAS during pregnancy were linked with slightly higher body mass index (BMI) in children and increased risk of obesity.

ECHO Study Suggests Exposure to PFAS During Pregnancy May Be Linked to Lower Birthweights
March 2023
PFAS were found in almost all study participants, and participants with higher levels of PFAS in their blood were more likely to have babies born at lower birthweights compared to those with lower levels of PFAS exposure.

Resources

Visit these government sites to learn more about chemical exposure initiatives.

White House PFAS initiative

EPA PFAS Action Plan

EPA Get the Lead Out initiative 

Questions

For more information, please email the NIH at NIHKidsandEnvironment@od.nih.gov.
For media inquiries or to request an interview, contact Rebekah Yeager at rebekah.yeager@nih.gov

Read More ECHO Research Related to Chemical Exposures

Prenatal Exposure to Perfluorononanoic Acid (PFNA) May Be Linked to Autism-Related Traits in Children Read more

Phthalate Exposure During Pregnancy Linked With Genetic Changes in the Placenta Read more

Exposure to Certain Phthalates During Pregnancy May Affect Brain Development in Infant Girls Read more

Pregnant People Exposed to Variety of Chemicals and Some May Affect Birth Weights Read more

Pregnant People Are Exposed to Dangerous Chemicals Found in a Variety of Household Products Read more

Pregnant People Exposed to Various Chemicals, Including Chemicals in Personal Care Products and Consumer Goods Read more

PFAS Exposure During Pregnancy Linked to Lower Birth Weight for Black Mothers Read more