ECHO Researchers Explore How Study Results Can Help Pregnant Mothers Take Action to Reduce Chemical Exposures

Collaborative ECHO research led by Amy Padula, PhD, MSc from the University of California, San Francisco and Rachel Morello-Frosch, PhD, MPH from the University of California, Berkeley found that many ECHO participants are motivated to engage in individual and collective action to protect their families and communities from the negative effects of chemical exposures. These findings may be used to improve report-back of chemical results and shift responsibility of chemical exposures from individuals to policymakers.

“When it comes to chemical exposure results, participants were interested in receiving timely, accessible, and straightforward information on how to reduce chemical exposures at the personal and community level,” said Dr. Padula.

This research, titled “Perspectives of peripartum people on opportunities for personal and collective action to reduce exposure to everyday chemicals: Focus groups to inform exposure report-back,” is published in Environmental Research.

In the summer of 2020, the researchers held three online focus groups with a diverse set of 18 mothers from ECHO pregnancy cohorts in Illinois and California. Focus groups, held in both English and Spanish, involved discussions around knowledge of chemical exposures and their sources, chemical exposure report-back preferences, and participants’ interest and willingness to engage in collective action.

Study results demonstrate the usefulness of chemical exposure report-back tools, like the Digital Exposure Report Back Interface (DERBI), for informing and empowering research participants. “Report-back can provide opportunities for participants to learn more about environmental health and how to lower exposure both in their homes and in their communities,” said Dr. Padula.

The next steps for this research include examining surveys from participants who are using DERBI to learn about their chemical exposures. These surveys may reveal more about how chemical exposure reports influence participant engagement with collective action efforts. Drs. Padula and Morello-Frosch encourage other ECHO cohorts to use DERBI to report back individual chemical results to their participants.

More information about the Digital Exposure Report Back Interface (DERBI) or how to use DERBI in your cohort, please visit the Silent Spring Institute website.

Read the Research Summary.

ECHO Study Identifies Biological, Behavioral, and Social Factors Affecting Pregnancy Health

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ECHO Study Identifies Biological, Behavioral, and Social Factors Affecting Pregnancy Health

Authors: Stephanie Eick, Rachel Morello-Frosch, et al.

 

Who sponsored this study?

This research was supported by the Environmental influences on Child Health Outcomes (ECHO) program, Office of The Director, National Institutes of Health.

 

What were the study results?

Pregnant participants who were over 30 years old and had a college degree had lower levels of oxidative stress. Levels of oxidative stress were higher among pregnant participants who were overweight or obese and unmarried. Also, current smokers or those with less than a high school education had higher levels of a oxidative stress biomarker. These results help identify how social, biologic, and behavioral factors may contribute to poor health in mothers and children.

 

Footnote: Results reported here are for a single study. Other or future studies may provide new information or different results. You should not make changes to your health without first consulting your healthcare professional.

 

What was the study's impact?

This is the largest study to date looking at the relationship between biological, social, and behavioral factors and oxidative stress during pregnancy. The results of this study provide important clues into how socioeconomic inequalities can contribute to poor health in pregnant women. This study may also inform future studies looking at risk factors for preterm birth.

 

Why was this study needed?

There is little data on what can cause oxidative stress during pregnancy. Oxidative stress is a process that can trigger cell damage and it is thought to play a role in the development of some diseases. By identifying biological, behavioral, and socioeconomic factors in a mother’s day-to-day life that may lead to increased risk for oxidative stress, research can help inform the development of targeted strategies for the prevention of poor prenatal health outcomes.

 

Who was involved?

This study involved approximately 2,000 pregnant participants in the mainland United States and Puerto Rico who were enrolled in one of four ECHO cohorts.

 

What happened during the study?

Researchers collected urine samples from participants and measured the levels of biomarkers for oxidative stress. Researchers calculated how levels of oxidative stress biomarkers changed in response to biological, behavioral, and social factors. Maternal age, pre-pregnancy body mass index, marital/partnered status, parity, and smoking status were included as biological and behavioral factors while race/ethnicity, maternal education, and stressful life events were considered social factors.

 

What happens next?

The research team is examining the impact of oxidative stress on adverse pregnancy outcomes, such as preterm birth.

 

Where can I learn more?

The full journal article, titled “Associations between social, biologic, and behavioral factors and biomarkers of oxidative stress during pregnancy: Findings from four ECHO cohorts” is published in Science of the Total Environment.

 

The content is the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Published April 29, 2022

Access the associated article.

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Informed Mothers More Likely to Engage in Collective Action, Reduce Family- and Community-Level Chemical Exposures

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Informed Mothers More Likely to Engage in Collective Action, Reduce Family- and Community-Level Chemical Exposures

Authors: Amy Padula, Rachel Morello-Frosch, et al.

 

Who sponsored this study?

This research was supported by the Environmental influences on Child Health Outcomes (ECHO) program, the Office of the Director, and the National Institutes of Health.

 

What were the study results?

This study found that participants knew about the dangers of chemical exposures and were motivated to act to protect the health of their families and communities, although they have busy family lives, and the pandemic has further prevented them from participating in collective action. Participants requested strategies that were time-efficient and included straightforward, accessible information on how to reduce exposures at the personal and community level.

Footnote: Results reported here are for a single study. Other or future studies may provide new information or different results. You should not make changes to your health without first consulting your healthcare professional.

 

What was the study's impact?

Researchers have an opportunity to directly learn from participants about how to improve the way in which chemical exposure results are reported in future studies. Report-back systems, or ways that study results are returned to participants, can present valuable information for participants about environmental health and how to lower chemical exposures in their homes and communities, and hold policy makers responsible for protecting parents and children from harmful chemical exposures. Researchers can use tools like the Digital Exposure Report Back Interface (DERBI) to give their participants access to individualized chemical results with information about how to take individual and collective action to reduce exposures.

 

Why was this study needed?

Participants in chemical exposure studies who receive reports on their personal exposures often look for information to reduce those exposures. Many chemical exposures are the result of policies, regulations, and practices, not individual behaviors and lifestyles. Individuals can address those policies and regulations through collective action, which is working with others to reach a common goal. Researchers wanted to understand the role of personal exposure reports in a participant’s interest in engagement in collective action.

 

Who was involved?

In summer 2020, the researchers held three online focus groups in English and Spanish with a diverse group of 18 participants from pregnancy cohorts in Illinois and California.

 

What happened during the study?

This study aimed to understand how much participants know about sources of potentially harmful chemical exposures and their experience and interest in participating in collective action. Focus group participants talked about some of the barriers and strategies to participating in collective action, and their preferences for receiving and using their personalized reports about environmental chemical exposures. Input from these focus groups can be used to help design tools and content to report results of exposure research to ECHO participants.

 

What happens next?

The researchers are currently studying participant surveys from before and after participants received their chemical exposure reports to learn more about how participants use DERBI. These surveys may also reveal how DERBI reports may influence participant efforts to reduce exposure in their homes and communities through collective action.

 

Where can I learn more?

More information about the Digital Exposure Report Back Interface (DERBI) can be found on the Silent Spring Institute website.

Access the full journal article, titled “Perspectives of peripartum people on opportunities for personal and collective action to reduce exposure to everyday chemicals: Focus groups to inform exposure report-back” in Environmental Research.

 

The content is the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Published March 26, 2022

Access the associated article.

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Author(s): Jessie P. Buckley, Tracey J. Woodruff, et al.

Effects of Metal Mixture Exposure During Pregnancy on Fetal Growth

Authors: Caitlin Howe, Margaret R. Karagas, et al.

Exposures to environmental chemicals and their effect on important molecules during pregnancy

Author(s): Brett T. Doherty, Megan E. Romano, et al.

Do chemicals that break down slowly in the environment affect how long it takes to become pregnant?  

Author(s): Linda Kahn, Alison Hipwell, Kim Harley, Pam Factor-Litvak, Michele Klein-Fedyshin, Christine Porucznik, Eva Siegel, Yeyi Zhu

A review of studies that look at whether exposure to common non-persistent chemicals in consumer products delays the time it takes to become pregnant

Author(s): Alison E. Hipwell, Linda G. Kahn, Pam Factor-Litvak, et al