Maximizing the Potential of Shed Teeth

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ECHO Workshop: Maximizing the Potential of Shed Teeth
April 22, 2026 | 10:00am - 4:15pm ET | Virtual Event

The Environmental influences on Child Health Outcomes (ECHO) Cohort Consortium collects naturally shed deciduous (baby) teeth as part of its research into how early environmental exposures affect child health. Deciduous teeth provide a unique resource to determine timing of certain exposures starting in utero.

In 2025, ECHO launched its Ancillary Studies process to allow investigators—both within and outside of ECHO—to apply to use ECHO biospecimens for research. The scientific community has responded with substantial interest in performing assays on shed teeth. However, some assays destroy the entire tooth. If the consortium conducted even a subset of the proposed studies, demand would quickly exceed the available supply.

This virtual workshop will bring together leading experts to discuss how to efficiently, rigorously, and collaboratively assay biospecimens like shed teeth across multiple studies—ensuring this finite resource generates the greatest possible scientific value.

Overall Goal
Identify strategies to maximize scientific data yield from shed deciduous teeth across multiple research projects.

Objectives

  1. Understand what reproducible, valid assays are available for studying early developmental exposures in shed deciduous teeth.
  2. Integrate expertise on efficient use of shed teeth assays across multiple projects.

Summary Agenda

10:00 – 10:15 am Welcome/Objectives of Workshop

Matt W. Gillman, MD, SM
Director of Environmental influences on Child Health Outcomes (ECHO) Program

   
10:15 – 12:00 pm Session 1 – Current Evidence and Future Potential for Shed Teeth Research
   
12:00 – 12:45 pm Lunch Break
   
12:45 – 2:25 pm Session 2 – Choosing Approaches for Tooth Analysis
   
2:25 – 2:40 pm Break
   
2:40 – 4:15 pm Session 3 – Strategies for Collaborative Use of Limited Biospecimens
   
4:00 – 4:15 pm Closing Remarks

Krista Zanetti, PhD, MPH, RDN
Program Officer, Environmental influences on Child Health Outcomes (ECHO) Program

Join Via Videocast

https://videocast.nih.gov/watch/5f4a38cd-2ece-11f1-82c0-124f0a52e769

To help guide the discussion, please submit questions or comments during the workshop using the form provided here:

Link: https://forms.office.com/g/9tfGi3N0wa

Questions

For additional information or registration questions, please contact: NIHKidsandEnvironment@od.nih.gov

Supported by the NIH

Workshop Organizing Committee

Margaret Grisius, D.D.S., National Institute of Dental and Craniofacial Research

Darci Johnson, M.P.H., National Institute on Drug Abuse

Susan Laessig, M.S., Ph.D., DABT, Environmental influences on Child Health Outcomes Program

Kimberly LeBlanc, Ph.D., National Institute on Drug Abuse

Jack Moye, M.D., Eunice Kennedy Shriver National Institute of Child Health and Human Development

Rebecca Rodriguez, Ph.D., M.S., National Institute of Diabetes and Digestive and Kidney Diseases

Zubaida Saifudeen, Ph.D., National Institute of Dental and Craniofacial Research

Krista Zanetti Ph.D., M.P.H, R.D.N., Environmental influences on Child Health Outcomes Program