The Early Life Microbiome and Disrupting Exposures

Key Takeaways*:

Dr. Dominguez-Bello noted that:

• During a vaginal birth, babies are exposed to dense bacterial communities, and throughout early childhood, they continue to be exposed to natural non-self microbes.
• In modern society, humans interfere with these natural microbe exposures. For example, many women are given antibiotics during pregnancy, and many babies are born via cesarian section (c-section).
• A pilot study has shown that vaginal seeding—which involves transferring vaginal fluids to a newborn’s skin, mouth, or nose—after a c-section may improve microbiome trajectories.
• The health of future generations will rely on a deep understanding of microbial biology and restoration.
• ECHO Cohort data and observational studies are a great opportunity to test hypotheses and generate more opportunities for research.

*The content presented in this webinar is the responsibility of the speaker and does not necessarily represent the official views of the National Institutes of Health.