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DTSTART;TZID=America/New_York:20210210T130000
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CREATED:20201222T201558Z
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UID:2876-1612962000-1612965600@echochildren.org
SUMMARY:O'Shea/Fry: Early Life Origins of Health Among Individuals Born Extremely Preterm
DESCRIPTION:Early Life Origins of Health Among Individuals Born Extremely Preterm\n\n\n\n\n\nECHO Discovery Summary\nPreterm Birth and Long-Term Health Outcomes \nECHO Researchers Dr. Michael O’Shea\, MD\, MPH of the UNC Chapel Hill Division of Neonatal-Perinatal Medicine and Dr. Rebecca Fry\, PhD of the UNC Gillings School of Global Public Health gave a presentation about the Extremely Low Gestational Age Newborn (ELGAN) study. Dr. O’Shea and Dr. Fry presented the objectives of the ELGAN study and its findings in their presentation on ‘Early Life Origins of Health Among Individuals Born Extremely Preterm’. \nThe ELGAN Cohort focuses on researching mechanisms that could link preterm birth to long-term health outcomes\, such as chronic health and developmental disorders. Through the ECHO Program\, ELGAN has been able to expand to obesity\, asthma\, positive health (well-being\, life satisfaction\, global health)\, blood pressure\, and renal (kidney) outcome areas. Dr. O’Shea provided an overview of the study\, which has followed more than 1\,000 babies born at least 3 months early\, between 2002 and 2004\, at 14 different hospitals in five states. The ELGAN study confirmed strong relationships between neonatal inflammation and neurodevelopmental outcomes\, an area of ECHO research. Researchers have previously established that neonatal inflammation is associated with a broad suite of children’s health outcomes. \nAnother goal of ELGAN is to research perinatal influences on child health. One of the organs that researchers focused on was the placenta\, which is important for the developing fetus. Dr. Fry emphasized that data from the study indicates placental weight is linked to both prenatal exposures and later life adverse health outcomes. This suggests the possibility that placenta epigenetics links early life exposures and later life outcome. \nELGAN is now studying the cohort’s teenagers’ health and well-being\, including reasoning skills\, behavior\, emotions\, sleep patterns\, and overall quality of life. A key conclusion that both presenters highlighted is that similar studies are needed for diverse socioeconomic contexts and more recent birth cohorts. This will help lead to more indicative data for further findings in this area of neonatal and perinatal research. You can learn more about the ELGAN study and its research by watching the presentation. \nSpeakers: \n \nMichael O’Shea\, MD\, MPH \nDivision of Neonatal-Perinatal Medicine \nUniversity of North Carolina at Chapel Hill \nSpeaker Bio: Michael O’Shea\, MD\, MPH\, received his undergraduate\, medical school\, and masters degrees\, as well as residency training in internal medicine and pediatrics at the University of North Carolina. He completed a fellowship in Neonatal-Perinatal Medicine at Duke University. \n  \n \nRebecca Fry\, PhD \nUNC Gillings School of Global Public Health \nSpeaker Bio:  \nDr. Rebecca Fry is the Carol Remmer Angle Distinguished Professor of Children’s Environmental Health at UNC-Chapel Hill. Dr. Fry is the Associate Chair in Environmental Sciences and Engineering at the Gillings School of Global Public Health\, the Director of the UNC Superfund Research Program\, and founding Director of the Institute for Environmental Health Solutions. Dr. Fry is trained in molecular biology with a MS\, and PHD from Tulane University and post-doctoral training at Massachusetts Institute of Technology. \nDate: Wednesday\, February 10 \, 1 to 2pm \nSlides
URL:https://echochildren.org/event/oshea-and-fry/
LOCATION:WebEx
CATEGORIES:neuro,pregnancy
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